A lvl 55 Clothcrafter could try this and maybe get some skill points. However, you'd probably not wanna try this till you're at least 60 and got a good chance of a successfull synth. Even then it's best to get support. That thread can be expensive. In order to get this as a HQ... I think one would have to be at least 85-90 Clothcraft and still have quite a bit of luck.