Yes, you really notice it at higher levels especially.
When you have 250+ resistance, Shell V, and Vallation active you will seriously notice it.
Monks, Warriors, and Ninjas could be getting hammered for 1300-2000 by something like Acheron Flame whilst you'd be unlucky to take anymore than 200 and not outright resist the Burn effect.
Very tempted to bring Rune Fencer to the next Achuka fight I come along to and seeing how I do there.
Edited, May 5th 2013 8:23pm by Tatham
Beyond this place of wrath and tears
Looms but the Horror of the shade,
And yet the menace of the years
Finds, and shall find, me unafraid.
It matters not how strait the gate,
How charged with punishments the scroll.
I am the master of my fate:
I am the captain of my soul.
Invictus -- William Ernest Henley