I've been making slow, but steady profit on these.
Reishi mushrooms go for 20k a stack on Pandy, Hecteyes usually 1-4k, sage goes for approximately 200 gil a piece (4.8k for 2 stacks give or take), crystals 2k, and water is dirt cheap so usally what i'll spend is 28k for ingredients. These sell at the lowest 5k each, so I make at least 60k per stack of ingredients, so 32k profit. I skill up very well on these on firesday during full moon phases and facing SW (I'm 76.7 at time of post), sometimes 0.5 skillups per stack. Unfortunately these rarely sell outside Jueno so I'd get myself a mule there (if you haven't already), and sell 6 yourself and have your mule sell the other 6. When you log back in the next day you'll be looking at 30-40k in each delivery box.